Catálogo de publicaciones - revistas
Science
Resumen/Descripción – provisto por la editorial
No disponible.
Palabras clave – provistas por la editorial
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Disponibilidad
| Institución detectada | Período | Navegá | Descargá | Solicitá |
|---|---|---|---|---|
| No detectada | desde mar. 1997 / hasta dic. 2023 | Science Journals |
Información
Tipo de recurso:
revistas
ISSN impreso
0036-8075
ISSN electrónico
1095-9203
Editor responsable
American Association for the Advancement of Science (AAAS)
País de edición
Estados Unidos
Fecha de publicación
1880-
Cobertura temática
Tabla de contenidos
Radar spots trillions of unseen insects migrating above us
Elizabeth Pennisi
Palabras clave: Multidisciplinary.
Pp. No disponible
Special series on the new Congress: Meet Ro Khanna, representing the heart of Silicon Valley
Jeffrey Mervis
Palabras clave: Multidisciplinary.
Pp. No disponible
Special series on the new Congress: After 16 years of lawmaking, science ally Mike Honda departs
Jeffrey Mervis
Palabras clave: Multidisciplinary.
Pp. No disponible
Updated: FDA approves drug that rescues babies with fatal neurodegenerative disease
Meredith Wadman
Palabras clave: Multidisciplinary.
Pp. No disponible
Top stories: The Breakthrough of the Year, a heartbreaking ghost octopus story, and how pregnancy reshapes women’s brains
Jessica Boddy
Palabras clave: Multidisciplinary.
Pp. No disponible
Spatiotemporal antagonism in mesenchymal-epithelial signaling in sweat versus hair fate decision
Catherine P. Lu; Lisa Polak; Brice E. Keyes; Elaine Fuchs
<jats:title>How to grow hair or sweat glands</jats:title> <jats:p> Unlike other mammals that must pant or seek shade or water when overheated, humans are able to self-cool to tolerate extreme heat. Sweat glands, which enable humans to run in marathons, are instrumental for this remarkable feat. Lu <jats:italic>et al.</jats:italic> investigated skin appendage diversity during development of the furry backs and sweaty paws of mice (see the Perspective by Lai and Chuong). They also examined human skin, which is capable of making both hairs and sweat glands in the same area of the body. Epithelialmesenchymal interactions, with varied signaling pathways that act at specific times in development, are key to producing different skin appendages for adaptation to the environment. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" related-article-type="in-this-issue" xlink:href="10.1126/science.aah6102">10.1126/science.aah6102</jats:related-article> ; see also p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6319" page="1533" related-article-type="in-this-issue" vol="354" xlink:href="10.1126/science.aal4572">1533</jats:related-article> </jats:p>
Palabras clave: Multidisciplinary.
Pp. No disponible
Genetic identification of familial hypercholesterolemia within a single U.S. health care system
Noura S. Abul-Husn; Kandamurugu Manickam; Laney K. Jones; Eric A. Wright; Dustin N. Hartzel; Claudia Gonzaga-Jauregui; Colm O’Dushlaine; Joseph B. Leader; H. Lester Kirchner; D’Andra M. Lindbuchler; Marci L. Barr; Monica A. Giovanni; Marylyn D. Ritchie; John D. Overton; Jeffrey G. Reid; Raghu P. R. Metpally; Amr H. Wardeh; Ingrid B. Borecki; George D. Yancopoulos; Aris Baras; Alan R. Shuldiner; Omri Gottesman; David H. Ledbetter; David J. Carey; Frederick E. Dewey; Michael F. Murray
<jats:title>Unleashing the power of precision medicine</jats:title> <jats:p> Precision medicine promises the ability to identify risks and treat patients on the basis of pathogenic genetic variation. Two studies combined exome sequencing results for over 50,000 people with their electronic health records. Dewey <jats:italic>et al.</jats:italic> found that ∼3.5% of individuals in their cohort had clinically actionable genetic variants. Many of these variants affected blood lipid levels that could influence cardiovascular health. Abul-Husn <jats:italic>et al.</jats:italic> extended these findings to investigate the genetics and treatment of familial hypercholesterolemia, a risk factor for cardiovascular disease, within their patient pool. Genetic screening helped identify at-risk patients who could benefit from increased treatment. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" related-article-type="in-this-issue" xlink:href="10.1126/science.aaf6814">10.1126/science.aaf6814</jats:related-article> , p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" related-article-type="in-this-issue" xlink:href="10.1126/science.aaf7000">10.1126/science.aaf7000</jats:related-article> </jats:p>
Palabras clave: Multidisciplinary.
Pp. No disponible
Distribution and clinical impact of functional variants in 50,726 whole-exome sequences from the DiscovEHR study
Frederick E. Dewey; Michael F. Murray; John D. Overton; Lukas Habegger; Joseph B. Leader; Samantha N. Fetterolf; Colm O’Dushlaine; Cristopher V. Van Hout; Jeffrey Staples; Claudia Gonzaga-Jauregui; Raghu Metpally; Sarah A. Pendergrass; Monica A. Giovanni; H. Lester Kirchner; Suganthi Balasubramanian; Noura S. Abul-Husn; Dustin N. Hartzel; Daniel R. Lavage; Korey A. Kost; Jonathan S. Packer; Alexander E. Lopez; John Penn; Semanti Mukherjee; Nehal Gosalia; Manoj Kanagaraj; Alexander H. Li; Lyndon J. Mitnaul; Lance J. Adams; Thomas N. Person; Kavita Praveen; Anthony Marcketta; Matthew S. Lebo; Christina A. Austin-Tse; Heather M. Mason-Suares; Shannon Bruse; Scott Mellis; Robert Phillips; Neil Stahl; Andrew Murphy; Aris Economides; Kimberly A. Skelding; Christopher D. Still; James R. Elmore; Ingrid B. Borecki; George D. Yancopoulos; F. Daniel Davis; William A. Faucett; Omri Gottesman; Marylyn D. Ritchie; Alan R. Shuldiner; Jeffrey G. Reid; David H. Ledbetter; Aris Baras; David J. Carey
<jats:title>Unleashing the power of precision medicine</jats:title> <jats:p> Precision medicine promises the ability to identify risks and treat patients on the basis of pathogenic genetic variation. Two studies combined exome sequencing results for over 50,000 people with their electronic health records. Dewey <jats:italic>et al.</jats:italic> found that ∼3.5% of individuals in their cohort had clinically actionable genetic variants. Many of these variants affected blood lipid levels that could influence cardiovascular health. Abul-Husn <jats:italic>et al.</jats:italic> extended these findings to investigate the genetics and treatment of familial hypercholesterolemia, a risk factor for cardiovascular disease, within their patient pool. Genetic screening helped identify at-risk patients who could benefit from increased treatment. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" related-article-type="in-this-issue" xlink:href="10.1126/science.aaf6814">10.1126/science.aaf6814</jats:related-article> , p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" related-article-type="in-this-issue" xlink:href="10.1126/science.aaf7000">10.1126/science.aaf7000</jats:related-article> </jats:p>
Palabras clave: Multidisciplinary.
Pp. No disponible
Erratum for the Report “Local modulation of human brain responses by circadian rhythmicity and sleep debt” by V. Muto, M. Jaspar, C. Meyer, C. Kussé, S. L. Chellappa, C. Degueldre, E. Balteau, A. Shaffii-Le Bourdiec, A. Luxen, B. Middleton, S. N. Archer,
Palabras clave: Multidisciplinary.
Pp. No disponible
Cover stories: Making the Breakthrough of the Year cover
Palabras clave: Multidisciplinary.
Pp. 1497-1497