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Institución detectada Período Navegá Descargá Solicitá
No detectada desde mar. 1997 / hasta dic. 2023 Science Journals

Información

Tipo de recurso:

revistas

ISSN impreso

0036-8075

ISSN electrónico

1095-9203

Editor responsable

American Association for the Advancement of Science (AAAS)

País de edición

Estados Unidos

Fecha de publicación

Cobertura temática

Tabla de contenidos

Three-dimensional Ca 2+ imaging advances understanding of astrocyte biology

Erika BindocciORCID; Iaroslav SavtchoukORCID; Nicolas LiaudetORCID; Denise BeckerORCID; Giovanni CarrieroORCID; Andrea VolterraORCID

<jats:title>Glial calcium dynamics in space and time</jats:title> <jats:p> Astrocytes use calcium signals to process information received from neighboring brain cells and thus generate modulatory responses at the local or network level. Previous studies have relied on calcium imaging in line scans or in a single focal plane mostly focusing on the cell bodies of astrocytes. Bindocci <jats:italic>et al.</jats:italic> used more powerful scanners that can rapidly scan many focal planes. They combined this technique with advanced genetic tools for monitoring calcium gradients with high sensitivity, which allowed three-dimensional calcium imaging of a whole astrocyte. Most of the basal calcium activity occurred in the astrocyte processes, some in the endfeet, and only a small fraction actually in the cell bodies of astrocytes. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6339" page="eaai8185" related-article-type="in-this-issue" vol="356" xlink:href="10.1126/science.aai8185">eaai8185</jats:related-article> </jats:p>

Palabras clave: Multidisciplinary.

Pp. No disponible

Migration—the choices we face

Mohamed H. A. Hassan

<jats:p>More than 1 million refugees and migrants arrived in Europe in 2015, and nearly 390,000 more in 2016, many fleeing conflict in the Middle East and North Africa. European leaders have often accommodated the migrants with admirable generosity, even while facing stiff political opposition. Yet, if developed countries focus only on immediate domestic impacts of mass migration, they will miss a critical point: When thousands of people, including many researchers, leave their home countries, the exodus perpetuates instability in those countries and damages prospects for future development.</jats:p>

Palabras clave: Multidisciplinary.

Pp. 667-667

News at a glance

<jats:p>A roundup of weekly science policy and related news.</jats:p>

Palabras clave: Multidisciplinary.

Pp. 668-669

Plot to redefine the kilogram nears climax

Adrian Cho

<jats:p>Metrologists present data needed to switch to standard based on constant of nature.</jats:p>

Palabras clave: Multidisciplinary.

Pp. 670-671

Sea trash traps face doubts

Erik Stokstad

<jats:p>The Ocean Cleanup envisions launching a fleet of drifting garbage collectors into the North Pacific Gyre.</jats:p>

Palabras clave: Multidisciplinary.

Pp. 671-671

Paolo Macchiarini's academic afterlife in Russia ends

Alla Astakhova

<jats:p>Disgraced surgeon loses funding and job but won't face misconduct investigation.</jats:p>

Palabras clave: Multidisciplinary.

Pp. 672-673

Genome writing project confronts technology hurdles

Kelly Servick

<jats:p>Grand challenge founders seek advances in DNA synthesis.</jats:p>

Palabras clave: Multidisciplinary.

Pp. 673-674

Island extinctions weren't inevitable

April Reese

<jats:p>During the ice age, human colonizers often coexisted with vulnerable island fauna.</jats:p>

Palabras clave: Multidisciplinary.

Pp. 674-675

People on the move

Elizabeth Culotta

Palabras clave: Multidisciplinary.

Pp. 676-677

Busting myths of origin

Ann Gibbons

<jats:p>Despite their tales of origin, most people are the mixed descendants of many migrations.</jats:p>

Palabras clave: Multidisciplinary.

Pp. 678-681