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Disponibilidad
Institución detectada Período Navegá Descargá Solicitá
No detectada desde mar. 1997 / hasta dic. 2023 Science Journals

Información

Tipo de recurso:

revistas

ISSN impreso

0036-8075

ISSN electrónico

1095-9203

Editor responsable

American Association for the Advancement of Science (AAAS)

País de edición

Estados Unidos

Fecha de publicación

Cobertura temática

Tabla de contenidos

Fake caterpillars reveal the worst places in the world to be prey

Elizabeth Pennisi

Palabras clave: Multidisciplinary.

Pp. No disponible

Senators press interior nominee on science and climate

Kellie Lunney

Palabras clave: Multidisciplinary.

Pp. No disponible

As Ebola outbreak grows, question of using vaccine becomes more urgent

Jon Cohen

Palabras clave: Multidisciplinary.

Pp. No disponible

Rice plant engineered with a ‘tunable’ immune system could fight multiple diseases at once

Ryan Cross

Palabras clave: Multidisciplinary.

Pp. No disponible

Creationist geologist sues U.S. park service after it rejects request to collect samples in Grand Canyon

Amanda Reilly

Palabras clave: Multidisciplinary.

Pp. No disponible

Chemists may be zeroing in on chemical reactions that sparked the first life

Robert Service

Palabras clave: Multidisciplinary.

Pp. No disponible

DOE ends freeze on several ARPA-E grants

Jeffrey Mervis

Palabras clave: Multidisciplinary.

Pp. No disponible

Top stories: Immigrant bloodlines analyzed, illegal petunias destroyed, and superstar surgeon fired again

Ryan Cross

Palabras clave: Multidisciplinary.

Pp. No disponible

Ephrin B1–mediated repulsion and signaling control germinal center T cell territoriality and function

Peiwen LuORCID; Changming ShihORCID; Hai QiORCID

<jats:title>Guiding immune cells to the center</jats:title> <jats:p> Germinal centers (GCs) are the site of antibody affinity maturation. The GC response fundamentally depends on contact-dependent signal exchange between antigen-specific T and B lymphocytes. Lu <jats:italic>et al.</jats:italic> uncovered a repulsive guidance system that inhibits GC recruitment and retention of T follicular helper (T <jats:sub>FH</jats:sub> ) cells while simultaneously promoting their helper activities locally (see the Perspective by Moschovakis and Forster). This system comprises the GC-specific transmembrane ephrin B1 (EFNB1) molecule and two EFNB1 receptors—EPHB4 and EPHB6—expressed by activated T cells, including T <jats:sub>FH</jats:sub> cells. In the absence of EFNB1 on GC B cells or when EPHB6 was suppressed on T cells, inappropriately large numbers of T cells were recruited to and retained in the GC as a result of relaxed repulsion of T <jats:sub>FH</jats:sub> cells. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6339" page="eaai9264" related-article-type="in-this-issue" vol="356" xlink:href="10.1126/science.aai9264">eaai9264</jats:related-article> ; see also p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6339" page="703" related-article-type="in-this-issue" vol="356" xlink:href="10.1126/science.aan5222">703</jats:related-article> </jats:p>

Palabras clave: Multidisciplinary.

Pp. No disponible

Cover stories: Visualizing scientist migrations

Palabras clave: Multidisciplinary.

Pp. No disponible