Catálogo de publicaciones - revistas

<jats:title>Making a plan</jats:title> <jats:p> Until recently, planning for the future has generally been considered to be unique to humans. Studies in the past 10 years have suggested that apes and scrub jays are also able to make such plans. However, these studies—especially those in the birds—have been questioned. It has been argued that planning in foraging and natural tasks is not the same as planning in a more general way. Kabadayi <jats:italic>et al.</jats:italic> tested ravens with tasks designed to specifically assess their general planning abilities (see the Perspective by Boeckle and Clayton). Confirming their forward-planning abilities, the birds performed at least as well as apes and small children in this complex cognitive task. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6347" page="202" related-article-type="in-this-issue" vol="357" xlink:href="10.1126/science.aam8138">202</jats:related-article> ; see also p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6347" page="126" related-article-type="in-this-issue" vol="357" xlink:href="10.1126/science.aan8802">126</jats:related-article> </jats:p>

<jats:title>New York City rats provide a gift to virologists</jats:title> <jats:p> Despite the development of curative drugs for hepatitis C virus (HCV) infection, global eradication of HCV will likely require a prophylactic vaccine. Progress toward a vaccine has been impeded by the absence of mouse models suitable for studying the immune response to HCV. Billerbeck <jats:italic>et al.</jats:italic> found that a HCV-related virus isolated from New York City rats produces an infection in laboratory mice that shares several immunological features with human infections (see the Perspective by Klenerman and Barnes). Their initial analyses of the infected mice revealed that acute clearance of the virus was dependent on T cells but not on natural killer cells. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6347" page="204" related-article-type="in-this-issue" vol="357" xlink:href="10.1126/science.aal1962">204</jats:related-article> ; see also p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6347" page="129" related-article-type="in-this-issue" vol="357" xlink:href="10.1126/science.aao0184">129</jats:related-article> </jats:p>

<jats:title>Not-so-sweet DNA damage repaired</jats:title> <jats:p> Glyoxal and methylglyoxal, by-products of sugar metabolism that are present in all cells, can react with, and thus damage, DNA. Indeed, glycation of guanine (G) is as prevalent as the major product of oxidative damage in DNA, 8-oxo-dG. Richarme <jats:italic>et al.</jats:italic> show that both prokaryotes and eukaryotes have dedicated systems that specifically repair glycation damage (see the Perspective by Dingler and Patel). The parkinsonism-associated protein DJ-1/Park7 and its bacterial homologs Hsp31, YhbO, and YajL direct the enzymatic repair of damaged glycated bases in DNA. The proteins also clean up the more vulnerable pool of free nucleotides in the cell, which are more susceptible to glycation than the nucleotides within DNA. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6347" page="208" related-article-type="in-this-issue" vol="357" xlink:href="10.1126/science.aag1095">208</jats:related-article> ; see also p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6347" page="130" related-article-type="in-this-issue" vol="357" xlink:href="10.1126/science.aan8293">130</jats:related-article> </jats:p>

<jats:title>Intergenerational transcription taming</jats:title> <jats:p> Parents provide genetic information that guides the development of the offspring. Zenk <jats:italic>et al.</jats:italic> show that epigenetic information, in the form of the repressive mark H3K27me3, is also propagated to the offspring and regulates proper gene expression in the embryo. Preventing the propagation of maternally inherited H3K27me3 led to precocious gene activation and, ultimately, embryo lethality. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6347" page="212" related-article-type="in-this-issue" vol="357" xlink:href="10.1126/science.aam5339">212</jats:related-article> </jats:p>

<jats:p>A weekly roundup of information on newly offered instrumentation, apparatus, and laboratory materials of potential interest to researchers.</jats:p>