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Science
Resumen/Descripción – provisto por la editorial
No disponible.
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Disponibilidad
| Institución detectada | Período | Navegá | Descargá | Solicitá |
|---|---|---|---|---|
| No detectada | desde mar. 1997 / hasta dic. 2023 | Science Journals |
Información
Tipo de recurso:
revistas
ISSN impreso
0036-8075
ISSN electrónico
1095-9203
Editor responsable
American Association for the Advancement of Science (AAAS)
País de edición
Estados Unidos
Fecha de publicación
1880-
Cobertura temática
Tabla de contenidos
S1P-dependent interorgan trafficking of group 2 innate lymphoid cells supports host defense
Yuefeng Huang
; Kairui Mao; Xi Chen; Ming-an Sun; Takeshi Kawabe; Weizhe Li; Nicholas Usher; Jinfang Zhu; Joseph F. Urban; William E. Paul; Ronald N. Germain
<jats:title>Inflammatory ILC2s are itinerant sentinels</jats:title> <jats:p> Group 2 innate lymphoid cells (ILC2s) are a population of immune cells that play important roles in tissue homeostasis and barrier immunity to helminths. Recent work has suggested that ILC2s are primarily long-term residents of tissues that do not readily recirculate. Huang <jats:italic>et al.</jats:italic> now demonstrate, however, that these findings do not necessarily hold true for the interleukin-25 (IL-25)–responsive KLRG1 <jats:sup>hi</jats:sup> “inflammatory” ILC2 (iILC2) subset (see the Perspective by Mjösberg and Rao). In response to exogenous IL-25 or helminth infection, iILC2 precursors in the small intestinal lamina propria proliferate and alter their expression of sphingosine 1-phosphate (S1P) receptors. They then traffic to both lymphatic and nonlymphatic organs in a partly S1P-dependent manner, participating in vital anti-helminth and tissue repair responses. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6371" page="114" related-article-type="in-this-issue" vol="359" xlink:href="10.1126/science.aam5809">114</jats:related-article> ; see also p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6371" page="36" related-article-type="in-this-issue" vol="359" xlink:href="10.1126/science.aar4301">36</jats:related-article> </jats:p>
Palabras clave: Multidisciplinary.
Pp. 114-119
New Products
<jats:p>A weekly roundup of information on newly offered instrumentation, apparatus, and laboratory materials of potential interest to researchers.</jats:p>
Palabras clave: Multidisciplinary.
Pp. 120-120
The harassment tax
Lydia Zepeda
Palabras clave: Multidisciplinary.
Pp. 126-126
Meet the world’s first salad-eating shark
Elizabeth Pennisi
Palabras clave: Multidisciplinary.
Pp. No disponible
This edible sensor could reveal what our gut microbes are up to
Kelly Servick
Palabras clave: Multidisciplinary.
Pp. No disponible
U.S. rivers are getting saltier, potentially compromising drinking water
Roni Dengler
Palabras clave: Multidisciplinary.
Pp. No disponible
U.S. Interior Department to put academic, nonprofit grants through political review
Michael Doyle
Palabras clave: Multidisciplinary.
Pp. No disponible
Light pollution may promote the spread of West Nile virus
Elizabeth Pennisi
Palabras clave: Multidisciplinary.
Pp. No disponible
Hitchhiking barnacles could reveal migration routes of ancient whales
Elizabeth Pennisi
Palabras clave: Multidisciplinary.
Pp. No disponible
A powerful new weapon against drug-resistant bacteria was inspired by the human body
Kelly Servick
Palabras clave: Multidisciplinary.
Pp. No disponible