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Science

Resumen/Descripción – provisto por la editorial

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Palabras clave – provistas por la editorial

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Disponibilidad
Institución detectada Período Navegá Descargá Solicitá
No detectada desde mar. 1997 / hasta dic. 2023 Science Journals

Información

Tipo de recurso:

revistas

ISSN impreso

0036-8075

ISSN electrónico

1095-9203

Editor responsable

American Association for the Advancement of Science (AAAS)

País de edición

Estados Unidos

Fecha de publicación

Cobertura temática

Tabla de contenidos

Telescope array will spy on spy satellites, star surfaces and black holes

Adam Mann

Palabras clave: Multidisciplinary.

Pp. No disponible

Congress pushes for multibillion-dollar nuclear reactor that critics call a boondoggle

Adrian Cho

Palabras clave: Multidisciplinary.

Pp. No disponible

After outcry, Puerto Rico’s legislature spares statistical agency

Lizzie Wade

Palabras clave: Multidisciplinary.

Pp. No disponible

Crime scene DNA could be used to reveal a suspect’s age—and whether they have cancer

Matt Warren

Palabras clave: Multidisciplinary.

Pp. No disponible

Plan to amend biopiracy rules would ‘smother research,’ biologists warn

Kai Kupferschmidt

Palabras clave: Multidisciplinary.

Pp. No disponible

Watch how battles with bats give moths their flashy tails

Elizabeth Pennisi

Palabras clave: Multidisciplinary.

Pp. No disponible

A fence built to keep out wild dogs has dramatically altered the Australian landscape

Lakshmi Supriya

Palabras clave: Multidisciplinary.

Pp. No disponible

Top stories: cycling and climate change, hidden pharma payments, and cursing surgeons

Katie Langin

Palabras clave: Multidisciplinary.

Pp. No disponible

Structure basis for RNA-guided DNA degradation by Cascade and Cas3

Yibei XiaoORCID; Min LuoORCID; Adam E. Dolan; Maofu LiaoORCID; Ailong KeORCID

<jats:title>Target degradation of Type I CRISPR</jats:title> <jats:p> The CRISPR adaptive immune systems defend bacteria against invaders. Type I CRISPR-Cas systems, the most prevalent type, use a Cascade complex to search the target DNA that is then degraded by Cas3 protein. Xiao <jats:italic>et al.</jats:italic> report cryo–electron microscopy structures of the Type I-E Cascade/Cas3 complex in the pre– and post–DNA-nicking states. These structures reveal how Cas3 captures Cascade only in its correct conformation to reduce off-targeting and how Cas3 switches from the initial DNA-nicking mode to the processive DNA degradation mode. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" related-article-type="in-this-issue" xlink:href="10.1126/science.aat0839">eaat0839</jats:related-article> </jats:p>

Palabras clave: Multidisciplinary.

Pp. No disponible

Erratum for the Report “Aging and neurodegeneration are associated with increased mutations in single human neurons” by M. A. Lodato, R. E. Rodin, C. L. Bohrson, M. E. Coulter, A. R. Barton, M. Kwon, M. A. Sherman, C. M. Vitzthum, L. J. Luquette, C. N. Ya

Palabras clave: Multidisciplinary.

Pp. No disponible