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Science

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Institución detectada Período Navegá Descargá Solicitá
No detectada desde mar. 1997 / hasta dic. 2023 Science Journals

Información

Tipo de recurso:

revistas

ISSN impreso

0036-8075

ISSN electrónico

1095-9203

Editor responsable

American Association for the Advancement of Science (AAAS)

País de edición

Estados Unidos

Fecha de publicación

Cobertura temática

Tabla de contenidos

Minimal functional driver gene heterogeneity among untreated metastases

Johannes G. ReiterORCID; Alvin P. Makohon-Moore; Jeffrey M. GeroldORCID; Alexander HeydeORCID; Marc A. AttiyehORCID; Zachary A. KohutekORCID; Collin J. TokheimORCID; Alexia BrownORCID; Rayne M. DeBlasioORCID; Juliana Niyazov; Amanda ZuckerORCID; Rachel KarchinORCID; Kenneth W. KinzlerORCID; Christine A. Iacobuzio-DonahueORCID; Bert VogelsteinORCID; Martin A. NowakORCID

<jats:title>Metastatic drivers same as primary</jats:title> <jats:p> Treatment decisions for cancer patients are increasingly guided by analysis of the gene mutations that drive primary tumor growth. Relatively little is known about driver gene mutations in metastases, which cause most cancer-related deaths. Reiter <jats:italic>et al.</jats:italic> explored whether the growth of different metastatic lesions within an individual patient is fueled by the same or distinct gene mutations. In a study of 76 untreated metastases from 20 patients with different types of cancer, all metastases within a patient shared the same functional driver gene mutations. Thus, analysis of a single biopsy could help oncologists select the optimal therapy for patients with widespread metastatic disease. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6406" page="1033" related-article-type="in-this-issue" vol="361" xlink:href="10.1126/science.aat7171">1033</jats:related-article> </jats:p>

Palabras clave: Multidisciplinary.

Pp. 1033-1037

New Products

<jats:p>A weekly roundup of information on newly offered instrumentation, apparatus, and laboratory materials of potential interest to researchers.</jats:p>

Palabras clave: Multidisciplinary.

Pp. 1038-1038

Outsmarting our instruments

Sarah Anderson

Palabras clave: Multidisciplinary.

Pp. 1042-1042

A deadly pig disease raging in China is bound to spread to other Asian countries, experts warn

Dennis Normile

Palabras clave: Multidisciplinary.

Pp. No disponible

Monarchs that ‘drop out’ of the migration game pick up more parasites

Frankie Schembri

Palabras clave: Multidisciplinary.

Pp. No disponible

How to find the right place for your Ph.D. or postdoc

Elisabeth Pain

Palabras clave: Multidisciplinary.

Pp. No disponible

Fewer people are answering a U.S. agency’s citizenship query. That’s fueling fears for the 2020 census

Jeffrey Mervis

Palabras clave: Multidisciplinary.

Pp. No disponible

Fungi that live in cockroaches, oil paintings, and other bizarre places come to light in new report

Erik Stokstad

Palabras clave: Multidisciplinary.

Pp. No disponible

Controversial plastic trash collector begins maiden ocean voyage

Erik Stokstad

Palabras clave: Multidisciplinary.

Pp. No disponible

If you’ve had anesthesia, you can likely thank this veterinarian who just won a top science prize

Frankie Schembri

Palabras clave: Multidisciplinary.

Pp. No disponible