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Science
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Disponibilidad
| Institución detectada | Período | Navegá | Descargá | Solicitá |
|---|---|---|---|---|
| No detectada | desde mar. 1997 / hasta dic. 2023 | Science Journals |
Información
Tipo de recurso:
revistas
ISSN impreso
0036-8075
ISSN electrónico
1095-9203
Editor responsable
American Association for the Advancement of Science (AAAS)
País de edición
Estados Unidos
Fecha de publicación
1880-
Cobertura temática
Tabla de contenidos
Ig Nobel prizes honor do-it-yourself colonoscopies, a curious use for postage stamps, and other peculiar research
Frankie Schembri
Palabras clave: Multidisciplinary.
Pp. No disponible
New global study reveals the ‘staggering’ loss of forests caused by industrial agriculture
Erik Stokstad
Palabras clave: Multidisciplinary.
Pp. No disponible
Physicists’ search for rare Higgs boson pairs could yield new physics
Adrian Cho
Palabras clave: Multidisciplinary.
Pp. No disponible
Researchers reboot ambitious effort to sequence all vertebrate genomes, but challenges loom
Elizabeth Pennisi
Palabras clave: Multidisciplinary.
Pp. No disponible
Can brain-stimulating implants treat some severe cases of autism?
Ingrid Wickelgren
Palabras clave: Multidisciplinary.
Pp. No disponible
What NSF’s new diversity grants say about attempts to help minority students
Jeffrey Mervis
Palabras clave: Multidisciplinary.
Pp. No disponible
These books can offer career guidance and inspiration
Elisabeth Pain
Palabras clave: Multidisciplinary.
Pp. No disponible
NIH gets $2 billion boost in final 2019 spending bill
Jocelyn Kaiser
Palabras clave: Multidisciplinary.
Pp. No disponible
Top stories: a gene for marathons, piercing the haze on ammonia, and a health plan for the ‘Iceman’
Frankie Schembri
Palabras clave: Multidisciplinary.
Pp. No disponible
Asymmetric phosphoric acid–catalyzed four-component Ugi reaction
Jian Zhang
; Peiyuan Yu; Shao-Yu Li; He Sun; Shao-Hua Xiang; Jun (Joelle) Wang; Kendall N. Houk; Bin Tan
<jats:title>Steering together all four Ugi pieces</jats:title> <jats:p> The nearly 60-year-old Ugi reaction is a remarkably efficient means of linking together four molecular building blocks: an aldehyde, an amine, a carboxylic acid, and an isocyanide. Because each component is independently tunable, the reaction is especially well suited to the assembly of diverse compound libraries. However, stereoselectivity has been a challenge. Zhang <jats:italic>et al.</jats:italic> now show that chiral phosphoric acids can catalyze the four-component coupling with high enantioselectivity (see the Perspective by Riva). Theory suggests that a hydrogen-bonded complex involving the phosphoric acid and carboxylic acid sets the stereochemistry for isocyanide attack on an imine intermediate. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" related-article-type="in-this-issue" xlink:href="10.1126/science.aas8707">eaas8707</jats:related-article> ; see also p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6407" page="1072" related-article-type="in-this-issue" vol="361" xlink:href="10.1126/science.aau7497">1072</jats:related-article> </jats:p>
Palabras clave: Multidisciplinary.
Pp. No disponible