Catálogo de publicaciones - revistas
Science
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Disponibilidad
| Institución detectada | Período | Navegá | Descargá | Solicitá |
|---|---|---|---|---|
| No detectada | desde mar. 1997 / hasta dic. 2023 | Science Journals |
Información
Tipo de recurso:
revistas
ISSN impreso
0036-8075
ISSN electrónico
1095-9203
Editor responsable
American Association for the Advancement of Science (AAAS)
País de edición
Estados Unidos
Fecha de publicación
1880-
Cobertura temática
Tabla de contenidos
De novo design of self-assembling helical protein filaments
Hao Shen
; Jorge A. Fallas; Eric Lynch; William Sheffler; Bradley Parry; Nicholas Jannetty; Justin Decarreau; Michael Wagenbach; Juan Jesus Vicente; Jiajun Chen; Lei Wang; Quinton Dowling; Gustav Oberdorfer; Lance Stewart; Linda Wordeman; James De Yoreo; Christine Jacobs-Wagner; Justin Kollman; David Baker
<jats:title>Built to be reversible</jats:title> <jats:p> There has been some success in designing stable peptide filaments; however, mimicking the reversible assembly of many natural protein filaments is challenging. Dynamic filaments usually comprise independently folded and asymmetric proteins and using such building blocks requires the design of multiple intermonomer interfaces. Shen <jats:italic>et al.</jats:italic> report the design of self-assembling helical filaments based on previously designed stable repeat proteins. The filaments are micron scale, and their diameter can be tuned by varying the number of repeats in the monomer. Anchor and capping units, built from monomers that lack an interaction interface, can be used to control assembly and disassembly. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6415" page="705" related-article-type="in-this-issue" vol="362" xlink:href="10.1126/science.aau3775">705</jats:related-article> </jats:p>
Palabras clave: Multidisciplinary.
Pp. 705-709
New Products
<jats:p>A weekly roundup of information on newly offered instrumentation, apparatus, and laboratory materials of potential interest to researchers.</jats:p>
Palabras clave: Multidisciplinary.
Pp. 710-710
Finding peace with pencil
Brittany L. Forte
Palabras clave: Multidisciplinary.
Pp. 714-714
Spurred by sexual misconduct, grad student ‘zine’ documents efforts to improve department culture
Lily Cohen
Palabras clave: Multidisciplinary.
Pp. No disponible
In a paradox, obesity is a ‘net positive’ for cutting-edge anticancer drugs
Jocelyn Kaiser
Palabras clave: Multidisciplinary.
Pp. No disponible
Venus flytraps kill with chemicals like those from lightning bolts
Richard Lovett
Palabras clave: Multidisciplinary.
Pp. No disponible
Killing badgers not enough to defeat costly tuberculosis in cattle, U.K. report finds
Erik Stokstad
Palabras clave: Multidisciplinary.
Pp. No disponible
Large, strangely dim galaxy found lurking on far side of Milky Way
Adam Mann
Palabras clave: Multidisciplinary.
Pp. No disponible
Science restored: Eddie Bernice Johnson prepares to chair key panel in U.S. House of Representatives
Jeffrey Mervis
Palabras clave: Multidisciplinary.
Pp. No disponible
Reprogrammed cells could tackle brain damage
Kelly Servick
Palabras clave: Multidisciplinary.
Pp. No disponible