Catálogo de publicaciones - revistas
Science
Resumen/Descripción – provisto por la editorial
No disponible.
Palabras clave – provistas por la editorial
No disponibles.
Disponibilidad
| Institución detectada | Período | Navegá | Descargá | Solicitá |
|---|---|---|---|---|
| No detectada | desde mar. 1997 / hasta dic. 2023 | Science Journals |
Información
Tipo de recurso:
revistas
ISSN impreso
0036-8075
ISSN electrónico
1095-9203
Editor responsable
American Association for the Advancement of Science (AAAS)
País de edición
Estados Unidos
Fecha de publicación
1880-
Cobertura temática
Tabla de contenidos
Structure of the RNA-dependent RNA polymerase from COVID-19 virus
Yan Gao
; Liming Yan; Yucen Huang; Fengjiang Liu; Yao Zhao; Lin Cao; Tao Wang; Qianqian Sun; Zhenhua Ming; Lianqi Zhang; Ji Ge; Litao Zheng; Ying Zhang; Haofeng Wang; Yan Zhu; Chen Zhu; Tianyu Hu; Tian Hua; Bing Zhang; Xiuna Yang; Jun Li; Haitao Yang; Zhijie Liu; Wenqing Xu; Luke W. Guddat; Quan Wang; Zhiyong Lou; Zihe Rao
<jats:title>The COVID-19 RNA-synthesizing machine</jats:title> <jats:p> Many in the scientific community have mobilized to understand the virus that is causing the global coronavirus disease 2019 (COVID-19) pandemic. Gao <jats:italic>et al.</jats:italic> focused on a complex that plays a key role in the replication and transcription cycle of the virus. They used cryo–electron microscopy to determine a 2.9-angstrom-resolution structure of the RNA-dependent RNA polymerase nsp12, which catalyzes the synthesis of viral RNA, in complex with two cofactors, nsp7 and nsp8. nsp12 is a target for nucleotide analog antiviral inhibitors such as remdesivir, and the structure may provide a basis for designing new antiviral therapeutics. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6492" page="779" related-article-type="in-this-issue" vol="368" xlink:href="10.1126/science.abb7498">779</jats:related-article> </jats:p>
Palabras clave: Multidisciplinary.
Pp. 779-782
New Products
<jats:p>A weekly roundup of information on newly offered instrumentation, apparatus, and laboratory materials of potential interest to researchers.</jats:p>
Palabras clave: Multidisciplinary.
Pp. 783-783
Branching out as a mentor
Bob Hickey
Palabras clave: Multidisciplinary.
Pp. 786-786
Long-acting injectable drug prevents HIV infections
Jon Cohen
Palabras clave: Multidisciplinary.
Pp. No disponible
Mount St. Helens 40 years later: what we’ve learned, and still don’t know
Warren Cornwall
Palabras clave: Multidisciplinary.
Pp. No disponible
United States relaxes rules for biotech crops
Erik Stokstad
Palabras clave: Multidisciplinary.
Pp. No disponible
Open-access science funders announce price transparency rules for publishers
Nicholas Wallace
Palabras clave: Multidisciplinary.
Pp. No disponible
Why do some COVID-19 patients infect many others, whereas most don’t spread the virus at all?
Kai Kupferschmidt
Palabras clave: Multidisciplinary.
Pp. No disponible
NSF pushed to boost funding for dating and squeezing rocks
Paul Voosen
Palabras clave: Multidisciplinary.
Pp. No disponible
Cold War satellites inadvertently tracked species declines
Stephenie Livingston
Palabras clave: Multidisciplinary.
Pp. No disponible