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Institución detectada Período Navegá Descargá Solicitá
No detectada desde mar. 1997 / hasta dic. 2023 Science Journals

Información

Tipo de recurso:

revistas

ISSN impreso

0036-8075

ISSN electrónico

1095-9203

Editor responsable

American Association for the Advancement of Science (AAAS)

País de edición

Estados Unidos

Fecha de publicación

Cobertura temática

Tabla de contenidos

Changes in contact patterns shape the dynamics of the COVID-19 outbreak in China

Juanjuan ZhangORCID; Maria LitvinovaORCID; Yuxia LiangORCID; Yan Wang; Wei Wang; Shanlu Zhao; Qianhui Wu; Stefano Merler; Cécile ViboudORCID; Alessandro VespignaniORCID; Marco AjelliORCID; Hongjie YuORCID

<jats:title>Who and what next?</jats:title> <jats:p> The coronavirus 2019 (COVID-19) pandemic has brought tighter restrictions on the daily lives of millions of people, but we do not yet understand what measures are the most effective. Zhang <jats:italic>et al.</jats:italic> modeled virus transmission in Wuhan, China, in February 2020, investigating the effects of interventions ranging from patient management to social isolation. Age-mixing patterns were estimated by contact surveys conducted in Wuhan and Shanghai at the beginning of February 2020. Once people reduced their average daily contacts from 14 to 20 down to 2, transmission rapidly fell below the epidemic threshold. The model also showed that preemptive school closures helped to reduce transmission, although alone they would not prevent a COVID-19 outbreak. Limiting human mixing to within households appeared to be the most effective measure. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6498" page="1481" related-article-type="in-this-issue" vol="368" xlink:href="10.1126/science.abb8001">1481</jats:related-article> </jats:p>

Palabras clave: Multidisciplinary.

Pp. 1481-1486

Metalens-array–based high-dimensional and multiphoton quantum source

Lin LiORCID; Zexuan LiuORCID; Xifeng RenORCID; Shuming WangORCID; Vin-Cent Su; Mu-Ku ChenORCID; Cheng Hung ChuORCID; Hsin Yu KuoORCID; Biheng LiuORCID; Wenbo Zang; Guangcan Guo; Lijian ZhangORCID; Zhenlin WangORCID; Shining ZhuORCID; Din Ping TsaiORCID

<jats:title>Metalens-array–based quantum source</jats:title> <jats:p> Spontaneous down-conversion is an exotic optical process in a nonlinear crystal in which a high-energy photon splits into two lower-energy photons that are quantum mechanically entangled. These entangled pairs are valuable commodities for quantum information processing and quantum communications. Because the experimental setup is usually performed with bulk optical components, there is a need to decrease the size scale for application. Li <jats:italic>et al.</jats:italic> combined an array of specialized metalenses with a nonlinear crystal and show that the scale of the process can be shrunk substantially. The approach should prove useful for developing miniaturized integrated quantum optical technologies. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6498" page="1487" related-article-type="in-this-issue" vol="368" xlink:href="10.1126/science.aba9779">1487</jats:related-article> </jats:p>

Palabras clave: Multidisciplinary.

Pp. 1487-1490

Quieting a noisy antenna reproduces photosynthetic light-harvesting spectra

Trevor B. ArpORCID; Jed Kistner-MorrisORCID; Vivek AjiORCID; Richard J. CogdellORCID; Rienk van GrondelleORCID; Nathaniel M. GaborORCID

<jats:title>Pairs of peaks stabilize output power</jats:title> <jats:p> A counterintuitive feature of photosynthesis is that the primary pigments involved in absorbing light—for example, chlorophyll a and b in plants—do not all absorb right at the peak of the spectrum but instead are offset from the peak and each other. Arp <jats:italic>et al.</jats:italic> formulated a network model that explains how using pigments with this absorption-peak pattern can mitigate internal and external fluctuations in energy transfer, minimizing noise in output power (see the Perspective by Duffy). The model accurately reproduces absorption peaks for three diverse photosynthetic systems from different spectral environments. Such a mechanism may provide an underlying robustness to biological photosynthetic processes that can be further tuned and tweaked to adapt to longer-scale fluctuations in light intensity. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6498" page="1490" related-article-type="in-this-issue" vol="368" xlink:href="10.1126/science.aba6630">1490</jats:related-article> ; see also p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6498" page="1427" related-article-type="in-this-issue" vol="368" xlink:href="10.1126/science.abc8063">1427</jats:related-article> </jats:p>

Palabras clave: Multidisciplinary.

Pp. 1490-1495

Arctic-adapted dogs emerged at the Pleistocene–Holocene transition

Mikkel-Holger S. SindingORCID; Shyam GopalakrishnanORCID; Jazmín Ramos-MadrigalORCID; Marc de ManuelORCID; Vladimir V. PitulkoORCID; Lukas KudernaORCID; Tatiana R. FeuerbornORCID; Laurent A. F. FrantzORCID; Filipe G. VieiraORCID; Jonas NiemannORCID; Jose A. Samaniego Castruita; Christian CarøeORCID; Emilie U. Andersen-RanbergORCID; Peter D. JordanORCID; Elena Y. Pavlova; Pavel A. NikolskiyORCID; Aleksei K. KasparovORCID; Varvara V. IvanovaORCID; Eske WillerslevORCID; Pontus SkoglundORCID; Merete FredholmORCID; Sanne Eline WennerbergORCID; Mads Peter Heide-JørgensenORCID; Rune DietzORCID; Christian SonneORCID; Morten Meldgaard; Love DalénORCID; Greger LarsonORCID; Bent PetersenORCID; Thomas Sicheritz-PonténORCID; Lutz BachmannORCID; Øystein WiigORCID; Tomas Marques-BonetORCID; Anders J. HansenORCID; M. Thomas P. GilbertORCID

<jats:title>Sled dog arctic adaptations go far back</jats:title> <jats:p> Dogs have been used for sledding in the Arctic as far back as ∼9500 years ago. However, the relationships among the earliest sled dogs, other dog populations, and wolves are unknown. Sinding <jats:italic>et al.</jats:italic> sequenced an ancient sled dog, 10 modern sled dogs, and an ancient wolf and analyzed their genetic relationships with other modern dogs. This analysis indicates that sled dogs represent an ancient lineage going back at least 9500 years and that wolves bred with the ancestors of sled dogs and precontact American dogs. However, gene flow between sled dogs and wolves likely stopped before ∼9500 years ago. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6498" page="1495" related-article-type="in-this-issue" vol="368" xlink:href="10.1126/science.aaz8599">1495</jats:related-article> </jats:p>

Palabras clave: Multidisciplinary.

Pp. 1495-1499

Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir

Wanchao YinORCID; Chunyou Mao; Xiaodong LuanORCID; Dan-Dan ShenORCID; Qingya ShenORCID; Haixia SuORCID; Xiaoxi WangORCID; Fulai ZhouORCID; Wenfeng ZhaoORCID; Minqi GaoORCID; Shenghai ChangORCID; Yuan-Chao XieORCID; Guanghui TianORCID; He-Wei Jiang; Sheng-Ce TaoORCID; Jingshan ShenORCID; Yi JiangORCID; Hualiang JiangORCID; Yechun XuORCID; Shuyang ZhangORCID; Yan ZhangORCID; H. Eric XuORCID

<jats:title>A wrench in the works of COVID-19</jats:title> <jats:p> Understanding the inner workings of the virus that causes coronavirus disease 2019 (COVID-19) may help us to disrupt it. Yin <jats:italic>et al.</jats:italic> focused on the viral polymerase essential for replicating viral RNA. They determined a structure of the polymerase bound to RNA and to the drug remdesivir. Remdesivir mimics an RNA nucleotide building block and is covalently linked to the replicating RNA, which blocks further synthesis of RNA. The structure provides a template for designing improved therapeutics against the viral polymerase. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6498" page="1499" related-article-type="in-this-issue" vol="368" xlink:href="10.1126/science.abc1560">1499</jats:related-article> </jats:p>

Palabras clave: Multidisciplinary.

Pp. 1499-1504

The pressure to assimilate

Montrai Spikes

Palabras clave: Multidisciplinary.

Pp. 1506-1506

The line is forming for a COVID-19 vaccine. Who should be at the front?

Jon Cohen

Palabras clave: Multidisciplinary.

Pp. No disponible

Swine flu strain with human pandemic potential increasingly found in pigs in China

Jon Cohen

Palabras clave: Multidisciplinary.

Pp. No disponible

When dikes burst, salt marshes might lessen deadly flooding

Erik Stokstad

Palabras clave: Multidisciplinary.

Pp. No disponible

New White House rules restrict use of grant funding to deal with COVID-19 impacts

Jeffrey Mervis

Palabras clave: Multidisciplinary.

Pp. No disponible