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Science
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Disponibilidad
| Institución detectada | Período | Navegá | Descargá | Solicitá |
|---|---|---|---|---|
| No detectada | desde mar. 1997 / hasta dic. 2023 | Science Journals |
Información
Tipo de recurso:
revistas
ISSN impreso
0036-8075
ISSN electrónico
1095-9203
Editor responsable
American Association for the Advancement of Science (AAAS)
País de edición
Estados Unidos
Fecha de publicación
1880-
Cobertura temática
Tabla de contenidos
Ocean’s hidden heat measured with earthquake sounds
Paul Voosen
Palabras clave: Multidisciplinary.
Pp. No disponible
Pandemic inspires new push to shrink jails and prisons
Kelly Servick
Palabras clave: Multidisciplinary.
Pp. No disponible
These 120,000-year-old footprints offer early evidence for humans in Arabia
Ann Gibbons
Palabras clave: Multidisciplinary.
Pp. No disponible
I’m a scientist making a difference during the pandemic—as a letter carrier
Dennis Macejak
Palabras clave: Multidisciplinary.
Pp. No disponible
Meet the man who told Trump climate change is real
Anne C. Mulkern
Palabras clave: Multidisciplinary.
Pp. No disponible
Ig Nobel Prizes reward research on helium-huffing alligators and knives made of feces
Rasha Aridi
Palabras clave: Multidisciplinary.
Pp. No disponible
Brain-scanning backpack brings neuroscience into the real world
Rebekah Tuchscherer
Palabras clave: Multidisciplinary.
Pp. No disponible
COVID-19 data scandal prompts tweaks to elite journal’s review process
Kelly Servick
Palabras clave: Multidisciplinary.
Pp. No disponible
‘I’m worried about voters screwing up.’ Election scientist tackles 2020 U.S. vote
Warren Cornwall
Palabras clave: Multidisciplinary.
Pp. No disponible
Species-specific pace of development is associated with differences in protein stability
Teresa Rayon
; Despina Stamataki; Ruben Perez-Carrasco; Lorena Garcia-Perez
; Christopher Barrington
; Manuela Melchionda
; Katherine Exelby
; Jorge Lazaro
; Victor L. J. Tybulewicz
; Elizabeth M. C. Fisher
; James Briscoe
<jats:title>Setting the tempo for development</jats:title> <jats:p> Many animals display similarities in their organization (body axis, organ systems, and so on). However, they can display vastly different life spans and thus must accommodate different developmental time scales. Two studies now compare human and mouse development (see the Perspective by Iwata and Vanderhaeghen). Matsuda <jats:italic>et al.</jats:italic> studied the mechanism by which the human segmentation clock displays an oscillation period of 5 to 6 hours, whereas the mouse period is 2 to 3 hours. They found that biochemical reactions, including protein degradation and delays in gene expression processes, were slower in human cells compared with their mouse counterparts. Rayon <jats:italic>et al.</jats:italic> looked at the developmental tempo of mouse and human embryonic stem cells as they differentiate to motor neurons in vitro. Neither the sensitivity of cells to signals nor the sequence of gene-regulatory elements could explain the differing pace of differentiation. Instead, a twofold increase in protein stability and cell cycle duration in human cells compared with mouse cells was correlated with the twofold slower rate of human differentiation. These studies show that global biochemical rates play a major role in setting the pace of development. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6510" page="1450" related-article-type="in-this-issue" vol="369" xlink:href="10.1126/science.aba7668">1450</jats:related-article> , p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" related-article-type="in-this-issue" xlink:href="10.1126/science.aba7667">eaba7667</jats:related-article> ; see also p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6510" page="1431" related-article-type="in-this-issue" vol="369" xlink:href="10.1126/science.abe0953">1431</jats:related-article> </jats:p>
Palabras clave: Multidisciplinary.
Pp. No disponible