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Science

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Institución detectada Período Navegá Descargá Solicitá
No detectada desde mar. 1997 / hasta dic. 2023 Science Journals

Información

Tipo de recurso:

revistas

ISSN impreso

0036-8075

ISSN electrónico

1095-9203

Editor responsable

American Association for the Advancement of Science (AAAS)

País de edición

Estados Unidos

Fecha de publicación

Cobertura temática

Tabla de contenidos

Ocean’s hidden heat measured with earthquake sounds

Paul Voosen

Palabras clave: Multidisciplinary.

Pp. No disponible

Pandemic inspires new push to shrink jails and prisons

Kelly Servick

Palabras clave: Multidisciplinary.

Pp. No disponible

These 120,000-year-old footprints offer early evidence for humans in Arabia

Ann Gibbons

Palabras clave: Multidisciplinary.

Pp. No disponible

I’m a scientist making a difference during the pandemic—as a letter carrier

Dennis Macejak

Palabras clave: Multidisciplinary.

Pp. No disponible

Meet the man who told Trump climate change is real

Anne C. Mulkern

Palabras clave: Multidisciplinary.

Pp. No disponible

Ig Nobel Prizes reward research on helium-huffing alligators and knives made of feces

Rasha Aridi

Palabras clave: Multidisciplinary.

Pp. No disponible

Brain-scanning backpack brings neuroscience into the real world

Rebekah Tuchscherer

Palabras clave: Multidisciplinary.

Pp. No disponible

COVID-19 data scandal prompts tweaks to elite journal’s review process

Kelly Servick

Palabras clave: Multidisciplinary.

Pp. No disponible

‘I’m worried about voters screwing up.’ Election scientist tackles 2020 U.S. vote

Warren Cornwall

Palabras clave: Multidisciplinary.

Pp. No disponible

Species-specific pace of development is associated with differences in protein stability

Teresa RayonORCID; Despina Stamataki; Ruben Perez-Carrasco; Lorena Garcia-PerezORCID; Christopher BarringtonORCID; Manuela MelchiondaORCID; Katherine ExelbyORCID; Jorge LazaroORCID; Victor L. J. TybulewiczORCID; Elizabeth M. C. FisherORCID; James BriscoeORCID

<jats:title>Setting the tempo for development</jats:title> <jats:p> Many animals display similarities in their organization (body axis, organ systems, and so on). However, they can display vastly different life spans and thus must accommodate different developmental time scales. Two studies now compare human and mouse development (see the Perspective by Iwata and Vanderhaeghen). Matsuda <jats:italic>et al.</jats:italic> studied the mechanism by which the human segmentation clock displays an oscillation period of 5 to 6 hours, whereas the mouse period is 2 to 3 hours. They found that biochemical reactions, including protein degradation and delays in gene expression processes, were slower in human cells compared with their mouse counterparts. Rayon <jats:italic>et al.</jats:italic> looked at the developmental tempo of mouse and human embryonic stem cells as they differentiate to motor neurons in vitro. Neither the sensitivity of cells to signals nor the sequence of gene-regulatory elements could explain the differing pace of differentiation. Instead, a twofold increase in protein stability and cell cycle duration in human cells compared with mouse cells was correlated with the twofold slower rate of human differentiation. These studies show that global biochemical rates play a major role in setting the pace of development. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6510" page="1450" related-article-type="in-this-issue" vol="369" xlink:href="10.1126/science.aba7668">1450</jats:related-article> , p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" related-article-type="in-this-issue" xlink:href="10.1126/science.aba7667">eaba7667</jats:related-article> ; see also p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6510" page="1431" related-article-type="in-this-issue" vol="369" xlink:href="10.1126/science.abe0953">1431</jats:related-article> </jats:p>

Palabras clave: Multidisciplinary.

Pp. No disponible