Catálogo de publicaciones - revistas

<jats:title>A dynamic viral spike</jats:title> <jats:p> Efforts to protect human cells against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have focused on the trimeric spike (S) protein. Several structures have shown a stabilized ectodomain of the spike in its prefusion conformation. Cai <jats:italic>et al.</jats:italic> now provide insight into the structural changes in the S protein that result in the fusion of the viral and host cell membranes. They purified full-length S protein and determined cryo–electron microscopy structures of both the prefusion and postfusion conformations. These structures add to our understanding of S protein function and could inform vaccine design. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6511" page="1586" related-article-type="in-this-issue" vol="369" xlink:href="10.1126/science.abd4251">1586</jats:related-article> </jats:p>

<jats:title> Duality of roaming mechanism in H <jats:sub>2</jats:sub> CO </jats:title> <jats:p> The phenomenon of roaming in chemical reactions (that is, bypassing the minimum energy pathway from unlikely geometries) has attracted a great deal of attention in the chemical reaction dynamics community over the past decade and still demonstrates unexpected results. Using velocity-map imaging of state-selected H <jats:sub>2</jats:sub> products of H <jats:sub>2</jats:sub> CO photodissociation, Quinn <jats:italic>et al.</jats:italic> discovered the bimodal structure of rotational distribution of the other product fragment, CO. Quasiclassical trajectories showed that this bimodality originates from two distinctive reaction pathways that proceed by the trans or cis configuration of O–C–H⋯H, leading to high or low rotational excitations of CO, respectively. Whether such a mechanism is present in the many other chemical reactions for which roaming reaction pathways have been reported is yet to be determined. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6511" page="1592" related-article-type="in-this-issue" vol="369" xlink:href="10.1126/science.abc4088">1592</jats:related-article> </jats:p>