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Disponibilidad
Institución detectada Período Navegá Descargá Solicitá
No detectada desde mar. 1997 / hasta dic. 2023 Science Journals

Información

Tipo de recurso:

revistas

ISSN impreso

0036-8075

ISSN electrónico

1095-9203

Editor responsable

American Association for the Advancement of Science (AAAS)

País de edición

Estados Unidos

Fecha de publicación

Cobertura temática

Tabla de contenidos

Not such identical twins

Caroline Ash; Jesse Smith (eds.)

Palabras clave: Multidisciplinary.

Pp. 581.3-582

RNA fold into life

Caroline Ash; Jesse Smith (eds.)

Palabras clave: Multidisciplinary.

Pp. 581.4-582

First Mo–Bi intermetallic material

Caroline Ash; Jesse Smith (eds.)

Palabras clave: Multidisciplinary.

Pp. 581.5-582

A cooler paint

Caroline Ash; Jesse Smith (eds.)

Palabras clave: Multidisciplinary.

Pp. 581.6-582

Lineage trajectories differ by mutation

Caroline Ash; Jesse Smith (eds.)

Palabras clave: Multidisciplinary.

Pp. 581.7-582

Role of iodine oxoacids in atmospheric aerosol nucleation

Xu-Cheng HeORCID; Yee Jun ThamORCID; Lubna DadaORCID; Mingyi WangORCID; Henning FinkenzellerORCID; Dominik StolzenburgORCID; Siddharth IyerORCID; Mario SimonORCID; Andreas KürtenORCID; Jiali Shen; Birte RörupORCID; Matti RissanenORCID; Siegfried SchobesbergerORCID; Rima BaalbakiORCID; Dongyu S. WangORCID; Theodore K. KoenigORCID; Tuija JokinenORCID; Nina SarnelaORCID; Lisa J. BeckORCID; João AlmeidaORCID; Stavros AmanatidisORCID; António AmorimORCID; Farnoush Ataei; Andrea BaccariniORCID; Barbara BertozziORCID; Federico BianchiORCID; Sophia Brilke; Lucía Caudillo; Dexian ChenORCID; Randall ChiuORCID; Biwu ChuORCID; António DiasORCID; Aijun DingORCID; Josef DommenORCID; Jonathan DuplissyORCID; Imad El HaddadORCID; Loïc Gonzalez Carracedo; Manuel Granzin; Armin HanselORCID; Martin HeinritziORCID; Victoria HofbauerORCID; Heikki JunninenORCID; Juha KangasluomaORCID; Deniz KemppainenORCID; Changhyuk KimORCID; Weimeng KongORCID; Jordan E. KrechmerORCID; Aleksander KvashinORCID; Totti Laitinen; Houssni LamkaddamORCID; Chuan Ping LeeORCID; Katrianne LehtipaloORCID; Markus LeimingerORCID; Zijun LiORCID; Vladimir MakhmutovORCID; Hanna E. ManninenORCID; Guillaume MarieORCID; Ruby MartenORCID; Serge Mathot; Roy L. MauldinORCID; Bernhard MentlerORCID; Ottmar Möhler; Tatjana MüllerORCID; Wei NieORCID; Antti OnnelaORCID; Tuukka PetäjäORCID; Joschka Pfeifer; Maxim PhilippovORCID; Ananth RanjithkumarORCID; Alfonso Saiz-LopezORCID; Imre SalmaORCID; Wiebke ScholzORCID; Simone Schuchmann; Benjamin SchulzeORCID; Gerhard Steiner; Yuri Stozhkov; Christian TauberORCID; António ToméORCID; Roseline C. ThakurORCID; Olli Väisänen; Miguel Vazquez-PufleauORCID; Andrea C. WagnerORCID; Yonghong Wang; Stefan K. WeberORCID; Paul M. Winkler; Yusheng Wu; Mao XiaoORCID; Chao YanORCID; Qing YeORCID; Arttu YlisirniöORCID; Marcel Zauner-WieczorekORCID; Qiaozhi ZhaORCID; Putian ZhouORCID; Richard C. FlaganORCID; Joachim CurtiusORCID; Urs BaltenspergerORCID; Markku KulmalaORCID; Veli-Matti KerminenORCID; Theo Kurtén; Neil M. DonahueORCID; Rainer VolkamerORCID; Jasper KirkbyORCID; Douglas R. WorsnopORCID; Mikko SipiläORCID

<jats:title>Faster than expected</jats:title> <jats:p> Iodine species are one of only a handful of atmospheric vapors known to make new aerosol particles, which play a central role in controlling the radiative forcing of climate. He <jats:italic>et al.</jats:italic> report experimental evidence from the CERN Cosmics Leaving Outdoor Droplets, or CLOUD, chamber demonstrating that iodic acid and iodous acid rapidly form new particles and can compete with sulfuric acid in pristine regions. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6529" page="589" related-article-type="in-this-issue" vol="371" xlink:href="10.1126/science.abe0298">589</jats:related-article> </jats:p>

Palabras clave: Multidisciplinary.

Pp. 589-595

Fecal microbiota transplant overcomes resistance to anti–PD-1 therapy in melanoma patients

Diwakar DavarORCID; Amiran K. Dzutsev; John A. McCullochORCID; Richard R. RodriguesORCID; Joe-Marc ChauvinORCID; Robert M. MorrisonORCID; Richelle N. Deblasio; Carmine Menna; Quanquan Ding; Ornella PaglianoORCID; Bochra Zidi; Shuowen ZhangORCID; Jonathan H. BadgerORCID; Marie VetizouORCID; Alicia M. ColeORCID; Miriam R. FernandesORCID; Stephanie PrescottORCID; Raquel G. F. CostaORCID; Ascharya K. BalajiORCID; Andrey MorgunORCID; Ivan Vujkovic-CvijinORCID; Hong WangORCID; Amir A. BorhaniORCID; Marc B. SchwartzORCID; Howard M. DubnerORCID; Scarlett J. Ernst; Amy Rose; Yana G. NajjarORCID; Yasmine BelkaidORCID; John M. KirkwoodORCID; Giorgio TrinchieriORCID; Hassane M. ZarourORCID

<jats:title>New fecal microbiota for cancer patients</jats:title> <jats:p> The composition of the gut microbiome influences the response of cancer patients to immunotherapies. Baruch <jats:italic>et al.</jats:italic> and Davar <jats:italic>et al.</jats:italic> report first-in-human clinical trials to test whether fecal microbiota transplantation (FMT) can affect how metastatic melanoma patients respond to anti–PD-1 immunotherapy (see the Perspective by Woelk and Snyder). Both studies observed evidence of clinical benefit in a subset of treated patients. This included increased abundance of taxa previously shown to be associated with response to anti–PD-1, increased CD8 <jats:sup>+</jats:sup> T cell activation, and decreased frequency of interleukin-8–expressing myeloid cells, which are involved in immunosuppression. These studies provide proof-of-concept evidence for the ability of FMT to affect immunotherapy response in cancer patients. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6529" page="602" related-article-type="in-this-issue" vol="371" xlink:href="10.1126/science.abb5920">602</jats:related-article> , p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6529" page="595" related-article-type="in-this-issue" vol="371" xlink:href="10.1126/science.abf3363">595</jats:related-article> ; see also p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6529" page="573" related-article-type="in-this-issue" vol="371" xlink:href="10.1126/science.abg2904">573</jats:related-article> </jats:p>

Palabras clave: Multidisciplinary.

Pp. 595-602

Fecal microbiota transplant promotes response in immunotherapy-refractory melanoma patients

Erez N. BaruchORCID; Ilan YoungsterORCID; Guy Ben-Betzalel; Rona OrtenbergORCID; Adi Lahat; Lior Katz; Katerina AdlerORCID; Daniela Dick-Necula; Stephen RaskinORCID; Naamah Bloch; Daniil RotinORCID; Liat Anafi; Camila Avivi; Jenny MelnichenkoORCID; Yael Steinberg-SilmanORCID; Ronac Mamtani; Hagit HaratiORCID; Nethanel AsherORCID; Ronnie Shapira-FrommerORCID; Tal Brosh-Nissimov; Yael EshetORCID; Shira Ben-Simon; Oren Ziv; Md Abdul Wadud KhanORCID; Moran Amit; Nadim J. AjamiORCID; Iris Barshack; Jacob Schachter; Jennifer A. WargoORCID; Omry KorenORCID; Gal MarkelORCID; Ben BoursiORCID

<jats:title>New fecal microbiota for cancer patients</jats:title> <jats:p> The composition of the gut microbiome influences the response of cancer patients to immunotherapies. Baruch <jats:italic>et al.</jats:italic> and Davar <jats:italic>et al.</jats:italic> report first-in-human clinical trials to test whether fecal microbiota transplantation (FMT) can affect how metastatic melanoma patients respond to anti–PD-1 immunotherapy (see the Perspective by Woelk and Snyder). Both studies observed evidence of clinical benefit in a subset of treated patients. This included increased abundance of taxa previously shown to be associated with response to anti–PD-1, increased CD8 <jats:sup>+</jats:sup> T cell activation, and decreased frequency of interleukin-8–expressing myeloid cells, which are involved in immunosuppression. These studies provide proof-of-concept evidence for the ability of FMT to affect immunotherapy response in cancer patients. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6529" page="602" related-article-type="in-this-issue" vol="371" xlink:href="10.1126/science.abb5920">602</jats:related-article> , p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6529" page="595" related-article-type="in-this-issue" vol="371" xlink:href="10.1126/science.abf3363">595</jats:related-article> ; see also p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6529" page="573" related-article-type="in-this-issue" vol="371" xlink:href="10.1126/science.abg2904">573</jats:related-article> </jats:p>

Palabras clave: Multidisciplinary.

Pp. 602-609

A hydrophobic FeMn@Si catalyst increases olefins from syngas by suppressing C1 by-products

Yanfei XuORCID; Xiangyang Li; Junhu Gao; Jie Wang; Guangyuan MaORCID; Xiaodong Wen; Yong Yang; Yongwang Li; Mingyue DingORCID

<jats:title>Keeping water away</jats:title> <jats:p> Syngas, a mixture of carbon monoxide (CO) and hydrogen, allows nonpetroleum resources such as biomass and natural gas to be converted to chemical products through Fischer-Tropsch synthesis. However, for the production of olefins, a key feedstock for other chemicals, about 50% of the CO is transformed to carbon dioxide and methane. Xu <jats:italic>et al.</jats:italic> decreased the selectivity for these undesired by-products to under 25% by modifying their catalyst, nanoparticles of iron doped with manganese and coated with a silica, with methyl groups (see the Perspective by Xie). This hydrophobic surface shortens the retention time of water on the catalyst surface to avoid the unwanted side reactions, and also suppresses oxidation of the metal carbide catalyst that forms under reaction conditions. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6529" page="610" related-article-type="in-this-issue" vol="371" xlink:href="10.1126/science.abb3649">610</jats:related-article> ; see also p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6529" page="577" related-article-type="in-this-issue" vol="371" xlink:href="10.1126/science.abg1750">577</jats:related-article> </jats:p>

Palabras clave: Multidisciplinary.

Pp. 610-613

A quantum-logic gate between distant quantum-network modules

Severin DaissORCID; Stefan LangenfeldORCID; Stephan Welte; Emanuele DistanteORCID; Philip Thomas; Lukas Hartung; Olivier Morin; Gerhard Rempe

<jats:title>Quantum gating at a distance</jats:title> <jats:p> The processing of quantum information is reliant on the encoding and manipulation of quantum states of a qubit. Superconducting circuits are the most advanced platform at present, but there is an issue with cross-talk between the qubits and the challenge of error correction as the systems are scaled up. Another approach being pursued is a modular platform in which the qubits are spatially separated. Daiss <jats:italic>et al.</jats:italic> demonstrate the operation of a quantum gate in which one qubit conditionally controls the state of another qubit spatially separated by 60 meters (see the Perspective by Hunger). Because the approach is platform independent, it could be extended from the demonstrated neutral atoms to ions, impurity vacancy centers, or even a combination of these qubits. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6529" page="614" related-article-type="in-this-issue" vol="371" xlink:href="10.1126/science.abe3150">614</jats:related-article> ; see also p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6529" page="576" related-article-type="in-this-issue" vol="371" xlink:href="10.1126/science.abg1536">576</jats:related-article> </jats:p>

Palabras clave: Multidisciplinary.

Pp. 614-617