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Nature

Resumen/Descripción – provisto por la editorial en inglés
Nature is a weekly international journal publishing the finest peer-reviewed research in all fields of science and technology on the basis of its originality, importance, interdisciplinary interest, timeliness, accessibility, elegance and surprising conclusions. Nature also provides rapid, authoritative, insightful and arresting news and interpretation of topical and coming trends affecting science, scientists and the wider public.
Palabras clave – provistas por la editorial

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Institución detectada Período Navegá Descargá Solicitá
No detectada desde jul. 2012 / hasta dic. 2023 Nature.com
No detectada desde jul. 2006 / hasta ago. 2012 Ovid

Información

Tipo de recurso:

revistas

ISSN impreso

0028-0836

ISSN electrónico

1476-4687

Editor responsable

Springer Nature

País de edición

Reino Unido

Fecha de publicación

Tabla de contenidos

Unconventional viral gene expression mechanisms as therapeutic targets

Jessica Sook Yuin Ho; Zeyu Zhu; Ivan MarazziORCID

Palabras clave: Multidisciplinary.

Pp. 362-371

Iron and nickel atoms in cometary atmospheres even far from the Sun

J. Manfroid; D. Hutsemékers; E. Jehin

Palabras clave: Multidisciplinary.

Pp. 372-374

Gaseous atomic nickel in the coma of interstellar comet 2I/Borisov

Piotr GuzikORCID; Michał DrahusORCID

Palabras clave: Multidisciplinary.

Pp. 375-378

Precision test of statistical dynamics with state-to-state ultracold chemistry

Yu LiuORCID; Ming-Guang HuORCID; Matthew A. NicholsORCID; Dongzheng YangORCID; Daiqian Xie; Hua GuoORCID; Kang-Kuen NiORCID

Palabras clave: Multidisciplinary.

Pp. 379-384

Tunable non-integer high-harmonic generation in a topological insulator

C. P. Schmid; L. Weigl; P. Grössing; V. JunkORCID; C. Gorini; S. Schlauderer; S. Ito; M. Meierhofer; N. Hofmann; D. AfanasievORCID; J. Crewse; K. A. KokhORCID; O. E. TereshchenkoORCID; J. Güdde; F. Evers; J. WilhelmORCID; K. Richter; U. Höfer; R. HuberORCID

Palabras clave: Multidisciplinary.

Pp. 385-390

Discovery, characterization and engineering of ligases for amide synthesis

Michael Winn; Michael Rowlinson; Fanghua Wang; Luis Bering; Daniel Francis; Colin Levy; Jason MicklefieldORCID

Palabras clave: Multidisciplinary.

Pp. 391-398

Overwintering fires in boreal forests

Rebecca C. ScholtenORCID; Randi JandtORCID; Eric A. MillerORCID; Brendan M. RogersORCID; Sander VeraverbekeORCID

Palabras clave: Multidisciplinary.

Pp. 399-404

Somatic mutation landscapes at single-molecule resolution

Federico AbascalORCID; Luke M. R. Harvey; Emily Mitchell; Andrew R. J. LawsonORCID; Stefanie V. Lensing; Peter Ellis; Andrew J. C. RussellORCID; Raul E. Alcantara; Adrian Baez-Ortega; Yichen WangORCID; Eugene Jing Kwa; Henry Lee-SixORCID; Alex CaganORCID; Tim H. H. CoorensORCID; Michael Spencer Chapman; Sigurgeir Olafsson; Steven Leonard; David JonesORCID; Heather E. Machado; Megan Davies; Nina F. Øbro; Krishnaa T. MahubaniORCID; Kieren Allinson; Moritz GerstungORCID; Kourosh Saeb-ParsyORCID; David G. Kent; Elisa LaurentiORCID; Michael R. StrattonORCID; Raheleh RahbariORCID; Peter J. CampbellORCID; Robert J. OsborneORCID; Iñigo MartincorenaORCID

Palabras clave: Multidisciplinary.

Pp. 405-410

Mouse prefrontal cortex represents learned rules for categorization

Sandra Reinert; Mark HübenerORCID; Tobias BonhoefferORCID; Pieter M. GoltsteinORCID

<jats:title>Abstract</jats:title><jats:p>The ability to categorize sensory stimuli is crucial for an animal’s survival in a complex environment. Memorizing categories instead of individual exemplars enables greater behavioural flexibility and is computationally advantageous. Neurons that show category selectivity have been found in several areas of the mammalian neocortex<jats:sup>1–4</jats:sup>, but the prefrontal cortex seems to have a prominent role<jats:sup>4,5</jats:sup> in this context. Specifically, in primates that are extensively trained on a categorization task, neurons in the prefrontal cortex rapidly and flexibly represent learned categories<jats:sup>6,7</jats:sup>. However, how these representations first emerge in naive animals remains unexplored, leaving it unclear whether flexible representations are gradually built up as part of semantic memory or assigned more or less instantly during task execution<jats:sup>8,9</jats:sup>. Here we investigate the formation of a neuronal category representation throughout the entire learning process by repeatedly imaging individual cells in the mouse medial prefrontal cortex. We show that mice readily learn rule-based categorization and generalize to novel stimuli. Over the course of learning, neurons in the prefrontal cortex display distinct dynamics in acquiring category selectivity and are differentially engaged during a later switch in rules. A subset of neurons selectively and uniquely respond to categories and reflect generalization behaviour. Thus, a category representation in the mouse prefrontal cortex is gradually acquired during learning rather than recruited ad hoc. This gradual process suggests that neurons in the medial prefrontal cortex are part of a specific semantic memory for visual categories.</jats:p>

Palabras clave: Multidisciplinary.

Pp. 411-417

Clofazimine broadly inhibits coronaviruses including SARS-CoV-2

Shuofeng Yuan; Xin YinORCID; Xiangzhi Meng; Jasper Fuk-Woo ChanORCID; Zi-Wei Ye; Laura Riva; Lars PacheORCID; Chris Chun-Yiu Chan; Pok-Man LaiORCID; Chris Chung-Sing Chan; Vincent Kwok-Man Poon; Andrew Chak-Yiu LeeORCID; Naoko Matsunaga; Yuan PuORCID; Chun-Kit Yuen; Jianli Cao; Ronghui Liang; Kaiming Tang; Li ShengORCID; Yushen DuORCID; Wan Xu; Chit-Ying Lau; Ko-Yung SitORCID; Wing-Kuk AuORCID; Runming WangORCID; Yu-Yuan Zhang; Yan-Dong Tang; Thomas Mandel Clausen; Jessica Pihl; Juntaek Oh; Kong-Hung Sze; Anna Jinxia ZhangORCID; Hin Chu; Kin-Hang KokORCID; Dong WangORCID; Xue-Hui Cai; Jeffrey D. Esko; Ivan Fan-Ngai Hung; Ronald Adolphus Li; Honglin ChenORCID; Hongzhe SunORCID; Dong-Yan JinORCID; Ren Sun; Sumit K. ChandaORCID; Kwok-Yung YuenORCID

Palabras clave: Multidisciplinary.

Pp. 418-423