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Nature
Resumen/Descripción – provisto por la editorial en inglés
Nature is a weekly international journal publishing the finest peer-reviewed research in all fields of science and technology on the basis of its originality, importance, interdisciplinary interest, timeliness, accessibility, elegance and surprising conclusions. Nature also provides rapid, authoritative, insightful and arresting news and interpretation of topical and coming trends affecting science, scientists and the wider public.Palabras clave – provistas por la editorial
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Disponibilidad
| Institución detectada | Período | Navegá | Descargá | Solicitá |
|---|---|---|---|---|
| No detectada | desde jul. 2012 / hasta dic. 2023 | Nature.com | ||
| No detectada | desde jul. 2006 / hasta ago. 2012 | Ovid |
Información
Tipo de recurso:
revistas
ISSN impreso
0028-0836
ISSN electrónico
1476-4687
Editor responsable
Springer Nature
País de edición
Reino Unido
Fecha de publicación
1869-
Tabla de contenidos
Unconventional viral gene expression mechanisms as therapeutic targets
Jessica Sook Yuin Ho; Zeyu Zhu; Ivan Marazzi
Palabras clave: Multidisciplinary.
Pp. 362-371
Iron and nickel atoms in cometary atmospheres even far from the Sun
J. Manfroid; D. Hutsemékers; E. Jehin
Palabras clave: Multidisciplinary.
Pp. 372-374
Gaseous atomic nickel in the coma of interstellar comet 2I/Borisov
Piotr Guzik
; Michał Drahus
Palabras clave: Multidisciplinary.
Pp. 375-378
Precision test of statistical dynamics with state-to-state ultracold chemistry
Yu Liu
; Ming-Guang Hu
; Matthew A. Nichols
; Dongzheng Yang
; Daiqian Xie; Hua Guo
; Kang-Kuen Ni
Palabras clave: Multidisciplinary.
Pp. 379-384
Tunable non-integer high-harmonic generation in a topological insulator
C. P. Schmid; L. Weigl; P. Grössing; V. Junk
; C. Gorini; S. Schlauderer; S. Ito; M. Meierhofer; N. Hofmann; D. Afanasiev
; J. Crewse; K. A. Kokh
; O. E. Tereshchenko
; J. Güdde; F. Evers; J. Wilhelm
; K. Richter; U. Höfer; R. Huber
Palabras clave: Multidisciplinary.
Pp. 385-390
Discovery, characterization and engineering of ligases for amide synthesis
Michael Winn; Michael Rowlinson; Fanghua Wang; Luis Bering; Daniel Francis; Colin Levy; Jason Micklefield
Palabras clave: Multidisciplinary.
Pp. 391-398
Overwintering fires in boreal forests
Rebecca C. Scholten
; Randi Jandt
; Eric A. Miller
; Brendan M. Rogers
; Sander Veraverbeke
Palabras clave: Multidisciplinary.
Pp. 399-404
Somatic mutation landscapes at single-molecule resolution
Federico Abascal
; Luke M. R. Harvey; Emily Mitchell; Andrew R. J. Lawson
; Stefanie V. Lensing; Peter Ellis; Andrew J. C. Russell
; Raul E. Alcantara; Adrian Baez-Ortega; Yichen Wang
; Eugene Jing Kwa; Henry Lee-Six
; Alex Cagan
; Tim H. H. Coorens
; Michael Spencer Chapman; Sigurgeir Olafsson; Steven Leonard; David Jones
; Heather E. Machado; Megan Davies; Nina F. Øbro; Krishnaa T. Mahubani
; Kieren Allinson; Moritz Gerstung
; Kourosh Saeb-Parsy
; David G. Kent; Elisa Laurenti
; Michael R. Stratton
; Raheleh Rahbari
; Peter J. Campbell
; Robert J. Osborne
; Iñigo Martincorena
Palabras clave: Multidisciplinary.
Pp. 405-410
Mouse prefrontal cortex represents learned rules for categorization
Sandra Reinert; Mark Hübener
; Tobias Bonhoeffer
; Pieter M. Goltstein
<jats:title>Abstract</jats:title><jats:p>The ability to categorize sensory stimuli is crucial for an animal’s survival in a complex environment. Memorizing categories instead of individual exemplars enables greater behavioural flexibility and is computationally advantageous. Neurons that show category selectivity have been found in several areas of the mammalian neocortex<jats:sup>1–4</jats:sup>, but the prefrontal cortex seems to have a prominent role<jats:sup>4,5</jats:sup> in this context. Specifically, in primates that are extensively trained on a categorization task, neurons in the prefrontal cortex rapidly and flexibly represent learned categories<jats:sup>6,7</jats:sup>. However, how these representations first emerge in naive animals remains unexplored, leaving it unclear whether flexible representations are gradually built up as part of semantic memory or assigned more or less instantly during task execution<jats:sup>8,9</jats:sup>. Here we investigate the formation of a neuronal category representation throughout the entire learning process by repeatedly imaging individual cells in the mouse medial prefrontal cortex. We show that mice readily learn rule-based categorization and generalize to novel stimuli. Over the course of learning, neurons in the prefrontal cortex display distinct dynamics in acquiring category selectivity and are differentially engaged during a later switch in rules. A subset of neurons selectively and uniquely respond to categories and reflect generalization behaviour. Thus, a category representation in the mouse prefrontal cortex is gradually acquired during learning rather than recruited ad hoc. This gradual process suggests that neurons in the medial prefrontal cortex are part of a specific semantic memory for visual categories.</jats:p>
Palabras clave: Multidisciplinary.
Pp. 411-417
Clofazimine broadly inhibits coronaviruses including SARS-CoV-2
Shuofeng Yuan; Xin Yin
; Xiangzhi Meng; Jasper Fuk-Woo Chan
; Zi-Wei Ye; Laura Riva; Lars Pache
; Chris Chun-Yiu Chan; Pok-Man Lai
; Chris Chung-Sing Chan; Vincent Kwok-Man Poon; Andrew Chak-Yiu Lee
; Naoko Matsunaga; Yuan Pu
; Chun-Kit Yuen; Jianli Cao; Ronghui Liang; Kaiming Tang; Li Sheng
; Yushen Du
; Wan Xu; Chit-Ying Lau; Ko-Yung Sit
; Wing-Kuk Au
; Runming Wang
; Yu-Yuan Zhang; Yan-Dong Tang; Thomas Mandel Clausen; Jessica Pihl; Juntaek Oh; Kong-Hung Sze; Anna Jinxia Zhang
; Hin Chu; Kin-Hang Kok
; Dong Wang
; Xue-Hui Cai; Jeffrey D. Esko; Ivan Fan-Ngai Hung; Ronald Adolphus Li; Honglin Chen
; Hongzhe Sun
; Dong-Yan Jin
; Ren Sun; Sumit K. Chanda
; Kwok-Yung Yuen
Palabras clave: Multidisciplinary.
Pp. 418-423