Catálogo de publicaciones - revistas

<jats:title>Up in smoke</jats:title> <jats:p> Extensive and intense wildfires in the Pacific Northwest of the United States in 2017 injected large quantities of smoke into the stratosphere. Yu <jats:italic>et al.</jats:italic> used satellite observations and modeling to characterize the history and chemistry of that smoke. The smoke rose to altitudes between 12 and 23 kilometers within 2 months owing to solar heating of black carbon. The smoke then remained in the stratosphere for more than 8 months. Photochemical loss of organic carbon resulted in a smoke lifetime 40% shorter than expected. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6453" page="587" related-article-type="in-this-issue" vol="365" xlink:href="10.1126/science.aax1748">587</jats:related-article> </jats:p>

<jats:title>Tetragonal phases for perovskite solar cells</jats:title> <jats:p> The power conversion efficiencies (PCEs) of all-inorganic perovskites are lower than those of materials with organic cations. This is in part because these materials have larger bandgaps. The cubic crystal phases of these materials also exhibit poor stability. Wang <jats:italic>et al.</jats:italic> synthesized the tetragonal β-phase of CsPbI <jats:sub>3</jats:sub> from HPbI <jats:sub>3</jats:sub> and CsI. The material exhibited higher stability and a more favorable bandgap, which allowed for PCEs of 15%. Passivation of the surface trap state with choline iodide boosted PCEs to 18%. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6453" page="591" related-article-type="in-this-issue" vol="365" xlink:href="10.1126/science.aav8680">591</jats:related-article> </jats:p>

<jats:title>Overlapping genes for synthetic biology</jats:title> <jats:p> Overlapping genes yield multiple distinct proteins when translated in alternative reading frames of the same nucleotide sequence. Blazejewski <jats:italic>et al.</jats:italic> developed a computational algorithm to predict de novo sequence entanglement and experimentally generated functional synthetic overlapping genes. When a sequence of interest was co-encoded with an essential gene in a living bacterium, its evolutionary stability substantially increased. When a gene of interest was synthetically overlapped with a toxin gene, its horizontal gene transfer frequency between bacteria was strongly suppressed. This generalizable strategy for designing, building, and testing overlapping genes helps stabilize vertical gene evolution and restrict horizontal gene flow. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6453" page="595" related-article-type="in-this-issue" vol="365" xlink:href="10.1126/science.aav5477">595</jats:related-article> </jats:p>

<jats:title>p53—still hazy after all these years?</jats:title> <jats:p> The gene encoding the p53 tumor suppressor protein is the most frequently mutated gene in human cancer. Yet decades after the gene's discovery, the biology of cancer-associated missense mutations in p53 is still being debated. Previous studies have suggested that missense mutations confer tumor-promoting functions to p53. Boettcher <jats:italic>et al.</jats:italic> conducted a detailed analysis of p53 missense mutations in human leukemia, drawing on methodologies including genome editing, a p53 saturation mutagenesis screen, mouse models, and clinical data (see the Perspective by Lane). They found no evidence that p53 missense mutations confer an oncogenic gain of function. Rather, the mutations exerted a dominant-negative effect that reduced the tumor suppressor activity of wild-type p53. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6453" page="599" related-article-type="in-this-issue" vol="365" xlink:href="10.1126/science.aax3649">599</jats:related-article> ; see also p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6453" page="539" related-article-type="in-this-issue" vol="365" xlink:href="10.1126/science.aay4319">539</jats:related-article> </jats:p>

<jats:title>Twisted bilayer graphene goes magnetic</jats:title> <jats:p> When two layers of graphene in a bilayer are twisted with respect to each other by just the right, “magic,” angle, the electrons in the system become strongly correlated. As the electronic density is tuned by gating, the system goes through several exotic phases, including superconductivity. Now, Sharpe <jats:italic>et al.</jats:italic> show that, at a particular electronic density, magic-angle graphene becomes magnetic (see the Perspective by Pixley and Andrei). The finding is supported by the observation of a large anomalous Hall effect. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6453" page="605" related-article-type="in-this-issue" vol="365" xlink:href="10.1126/science.aaw3780">605</jats:related-article> ; see also p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6453" page="543" related-article-type="in-this-issue" vol="365" xlink:href="10.1126/science.aay3409">543</jats:related-article> </jats:p>

<jats:p>A weekly roundup of information on newly offered instrumentation, apparatus, and laboratory materials of potential interest to researchers.</jats:p>